Precise gene editing technique changes one DNA base to correct heart disease

Precise Gene Editing Technique for Heart Disease

Faulty versions of the LMNA gene can cause various health issues, including heart muscle disease and muscle weakness.

Treatments exist, such as physical therapy and medication, but there are no cures.

A team of scientists, led by Eric Olson, developed a gene editing technique to correct genetic mutations.

Base editing has been used previously to correct other genetic heart diseases.

Author's summary: Gene editing technique corrects heart disease mutations.

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Medical Xpress Medical Xpress — 2025-10-14